It can be nearly impossible to remove an ink stain from clothing when a ballpoint pen explodes. Here's a resourceful way to treat the stain and make your clothes look as good as new: Cover the stain in hand sanitizer. Clear, gel-based hand sanitizers are loaded with alcohol, which help lift the stain from the fibers of clothes. Saturating the stain makes it easy for the stain to be removed when washed. Just allow the hand sanitizer to saturate for at least 10 minutes before washing.