health

Phantom Smells Often Linked to Damaged Nasal Cavity

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | June 1st, 2018

Dear Doctor: Last year, for four months, I smelled cigarette smoke all the time -- even though I wasn't near smokers. The problem went away, but now it's back. I can be in bed, in my kitchen, at the grocery store, even church. I have been diagnosed with benign paroxysmal positional vertigo. Is there a connection? If not, what's causing this?

Dear Reader: I can only imagine what a nuisance this is. The condition is called phantosmia, meaning the smelling of an odor that isn't actually there. Rest assured, you're not alone.

One survey of 3,603 people over the age of 40 found that 6 percent of people experience phantom odors. Another study, of 2,569 people ages 60 to 90, found that 4.9 percent reported phantosmia. The condition is more often reported by women than men, with many women having had a prior short-lived episode between the ages of 15 and 30. For the majority, the phantom odors are unpleasant, often described as the smell of something burned, spoiled, rotten or foul. Thus, the smell of cigarette smoke is not unusual. Symptoms can last from two minutes to 30 minutes at a time; fortunately, they're rarely chronic.

Phantosmia can have a variety of causes, some of them serious. The most common one is inflammation within the nasal cavity or within the sinuses. This is most likely in people who have chronic allergies or recurrent sinus infections, but the condition can also occur with nasal passage inflammation not related to allergies, such as that linked to exposure to solvents, ammonia, benzene, cigarette smoke and drugs inhaled through the nose.

Your diagnosis of benign paroxysmal positional vertigo could theoretically be linked to the condition in that this type of vertigo can be related to middle ear and Eustachian tube dysfunction, which in turn can be affected by nasal and sinus problems. Knowing whether you have a history of nasal congestion or sinus problems might shed light on this potential connection.

Trauma to the nose or the sinuses can also lead to phantosmia, as can head trauma that damages the areas of the brain that process smell. Speaking of the brain, the olfactory bulb located above the nasal cavity is full of nerves that send information about smell to the brain and, as we get older, this area can become damaged and lose many of its nerve cells. This loss can be especially significant in people with neurodegenerative diseases such as Alzheimer's, Parkinson's and Lewy Body dementia, all of which affect the olfactory bulb.

Blood pressure medications, such as beta blockers, calcium channel blockers and ACE inhibitors, can occasionally be linked to both loss of smell and phantosmia. Other potential causes include tumors within the brain or nasal cavity, as well as seizures.

Often, however, no cause can be found. This is termed idiopathic phantosmia and, on the plus side, it improves with time. In fact, 53 percent of patients have improvement or resolution of phantom smells after one year.

So, be encouraged that your symptoms could improve. In the meantime, try nasal rinses -- which could decrease the sense of phantom smells -- and work with your physician to identify, if possible, a cause for the problem.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

health

Scientists Still Learning How Fats Are Stored and Metabolized

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | May 31st, 2018

Dear Doctor: I hate dieting and have been putting off losing these last 12 pounds of baby weight. My husband says I should at least start exercising because it makes your fat healthier. Can this really be true?

Dear Reader: For all the bad press the fat within our bodies receives, it's actually a vital resource. With more than double the calories per gram than proteins or carbohydrates, it's an efficient system for storing energy that helped our ancient (and not-so-ancient) ancestors survive uncertain times. And while we tend to think of body fat in terms of its physical manifestation, as in the bulge of a waistline, it's actually a dynamic nutrient with multiple forms and functions within our bodies.

In addition to being an energy source, fat helps to manage temperature, cushion vital organs, regulate hormone production, build cell membranes and stockpile certain vitamins. It plays an important role in immune function and brain chemistry, as well as many other metabolic processes. Of course, too much stored fat is problematic, and can lead to adverse health consequences, including diabetes, heart disease and metabolic syndrome, to name just a few.

The complex cycle of how the various fats within our bodies are formed, stored, mobilized and metabolized is still not completely understood. (It's only a decade ago that we learned about the existence of "brown fat," which are fat cells within our bodies that burn rather than store lipids.) Now the results of recent studies have shed light on another question that has long puzzled scientists. That is, why do some overweight individuals develop insulin resistance, which is often a precursor to diabetes, and others do not?

One of the problems with stored fat is that it tends to release fatty acids into systemic circulation. This leads to inflammation, which is a common denominator in developing insulin resistance. But it turns out that not everyone who is overweight or obese has the same degree of release of fatty acids. A study last year from researchers at the University of Michigan found that certain individuals, despite being obese, have low rates of fatty acid release, few markers for inflammation and therefore do not develop insulin resistance. But why?

In a second study, the Michigan researchers looked at whether exercise might play a role. When they compared a group of overweight individuals who exercise regularly with a similar group of overweight individuals who did not exercise, they found that the subcutaneous fat of the active group contained more blood vessels. The two groups then took part in a session of aerobic exercise. Post-exercise biopsies of subcutaneous fat revealed that, after that single session, the stored fat in both groups became less "leaky," and this was considered healthier.

While it's important to note that these were both small studies, the results are intriguing. They add to what we already know about the health benefits of exercise and suggest some interesting directions for future study. In the meantime, we agree with your husband that no matter what you're doing with your diet, adding an exercise component to your daily life is a good idea.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

health

Using Public Restroom's Hand Dryer Spreads Bacteria Around

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | May 30th, 2018

Dear Doctor: Considering the recent news coverage of how hot-air hand dryers do little more than blow bacteria around, am I better off just wiping my hands on my pants when using a public restroom?

Dear Reader: First, let's consider why this would have seemed a ridiculous question only two decades ago -- before bathroom hand dryers had proliferated throughout the developed world. The use of paper towels in bathrooms had created concerns about environmental impact, both in connection to the trees used to make the paper towels and in the amount of trash produced. Bathroom hand dryers, although they used energy, decreased the use of, and trash from, paper towels -- not to mention they were (and remain) -- very cost-effective. The operation of bathroom hand dryers is only one-tenth to one-twentieth the cost of a year's worth of paper towels.

But, yes, now there are concerns about bathroom hand dryers and hygiene. In short, air hand dryers can aerosolize bacteria. A recent study at the University of Connecticut School of Medicine evaluated whether hand dryers contaminated the area around them with bacteria. The authors looked at three buildings within the school and placed bacterial growth plates (supplemented with sugar) in the bathrooms underneath the hand dryers. Each plate was placed 12 inches from the outlet of the hand dryer, left open to air for 2 minutes and then closed.

After 48 hours, the growth of bacteria was then measured. The plates near non-operating hand dryers grew 0 to 1 colony of bacteria. Those plates exposed to 30 seconds of air from operating hand dryers grew 18 to 60 colonies of bacteria, depending on the bathroom. That's a very big difference.

Multiple strains of bacteria, from 21 different species, were seen on the growth plates. The bacteria appeared not to come from the hand dryer itself, but from bacteria in the bathroom that was sucked into the air coming out of the fan. The reason: A high volume of air passes through these driers (19,000 linear feet per minute at the nozzle).

Two interesting notes: First, researchers saw no difference between women's and men's restrooms. Second, placing a HEPA filter within the hand dryer led to a fourfold reduction in the number of bacteria seen on the plates.

But because the hand dryers disperse bacteria does not necessarily mean they will increase the risk of infections, at least for most people. Those who have compromised immune systems, disruptions of the skin or intravenous lines, however, could potentially develop invasive infections. Furthermore, if you're washing your hands to prevent passing an infection to others, using a hand dryer may make the action moot. When you shake someone else's hand, you may transfer bacteria from the dryer air to them.

It may defeat the purpose of washing your hands in the first place, right? Not quite. The logic behind that conclusion is still hypothetical. A better study would be comparing the bacteria upon the hands of people who used either hand dryers or paper towels.

Until then, we're still not willing to suggest you dry your hands on your pants. It's simply better to use paper towels. Perhaps, sometime in the future, hand dryers with HEPA filters will become widely available.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

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