health

Diet, Exercise and Flexibility Training Can Alleviate OA Pain

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | July 26th, 2018

Dear Doctor: I just learned that the constant pain in my right knee, which I injured playing college basketball, is osteoarthritis. I'm only 33 and want to do everything I can to get better. Is it true that fish oil can help? Is there anything else I can do?

Dear Reader: Osteoarthritis, also referred to as OA, is a chronic degenerative condition that affects the joints. Unlike rheumatoid arthritis, which is an autoimmune disease, osteoarthritis is associated with the breakdown of the cartilage in the joints due, in large part, to wear and tear. Although OA is most common among people in their mid-60s and older, it can affect people of any age. A sports injury like yours is a significant risk factor for developing OA. So are chronic overuse, being overweight or obese, and genes. Both types of arthritis tend to be more common in women than in men.

OA most often affects the weight-bearing joints of the knees and hips. It can also affect the neck, spine, shoulders, elbows, hands and feet. Symptoms include joint stiffness, swelling, a reduced range of motion and pain. People with OA often report hearing clicking or popping sounds when they bend their joints. One side of the body is usually affected more than the other, perhaps because we tend to have a "stronger" side and unconsciously allow it to do more work.

Morning stiffness is a challenge and can require a half-hour or so of slow and deliberate activity to get the affected joints working freely. That stiffness typically returns after long periods of inactivity, like sitting at a desk at work, or remaining in the same position for extended period of times, such as when driving. Diagnosis is done through imaging tests like MRIs or X-rays, which can show the extent of damage that has taken place to the joint capsules.

With the findings from a recent study published in the journal Rheumatology, researchers from Great Britain added to the mounting evidence that nutrition and exercise play a role in managing the disease. An analysis of 68 studies about OA found that patients who took a low-dose supplement of fish oil of 1.5 capsules per day reported a measurable reduction of pain. The thinking is that the essential fatty acids in the fish oil help address the chronic inflammation that is part of the OA disease process.

Also important to managing OA was weight loss, which not only eased pressure on the joints but also led to a reduction in inflammation. In addition to a healthful diet of whole foods to reduce blood lipid levels, vitamin K, which is present in abundance in kale and spinach, was associated with positive outcomes. Vitamin K is required for the synthesis of certain proteins that help maintain the health of bones and connective tissues.

Finally -- and this can seem counterintuitive when dealing with the pain and stiffness of OA -- a gentle but consistent program of aerobic exercise, along with strength and flexibility training, proved to be important. None of this is a cure, but when undertaken together and incorporated into an ongoing lifestyle, living with OA can be a bit easier.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

health

Recent Study Suggests Dark Chocolate Can Improve Mood and Memory

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | July 25th, 2018

Dear Doctor: I have some dark chocolate every day and my (otherwise kind and loving) husband teases me for believing the news stories that chocolate is good for you. Please tell me that I haven't fallen for a bunch of quack science!

Dear Doctor: We can certainly understand how the idea that chocolate offers health benefits might spark a bit of skepticism. After all, when we hear about so-called superfoods, it's foods like kale, fish oil or green tea that tend to top the list. The idea that something as delicious as chocolate might be anything more than an indulgence takes a bit of getting used to. And yet you're right -- a number of studies have linked chocolate with a range of positive outcomes. The results of recent research suggest that chocolate improves memory and brain function, lowers blood pressure and cholesterol, can boost immunity and has a positive effect on mood.

But before you unwrap a chocolate bar in celebration, there's an important caveat. It's only dark chocolate that confers these positive effects. That is, chocolate with a minimum cacao concentration of 70 percent. That's because cacao is rich in chemical substances known as flavanols, which have potent antioxidant properties. Studies have shown that flavanols have a positive effect on connections between brain cells, offer protection from toxins and can shield the body from some of the damaging effects of inflammation.

The catch here is that in its pure state, cacao is relentlessly bitter. It's the sugar and fat that get added during manufacturing that give chocolate its sweetness and silky-smooth feel. For many people, the high levels of cacao needed for chocolate to become potentially beneficial render it unpalatable. If you're a lover of dark chocolate, though, you're in luck.

The results of two recent studies regarding dark chocolate, which were presented at the Experimental Biology 2018 annual meeting last April, back up many of the existing health claims about dark chocolate. (They also give you some recent data to use the next time you get teased for your chocolate-loving ways.) Researchers from Loma Linda University examined the brain scans of study participants before and after they ate 48 grams -- that's 1.7 ounces -- of dark chocolate. In the post-chocolate scans, they saw increased activity among certain immune cells in functions like T-cell activation, cellular immune response and in genes involved in neural signaling. That translates to beneficial effects on mood, memory, stress levels and inflammation. As with all studies that have a fairly small sample size, the findings here need further investigation to nail down the cause-and-effect of what the researchers saw.

Meanwhile, when you do eat chocolate, be sure to go for 70 percent cacao or higher. Natural chocolate has more flavanols than Dutch process, which uses alkali to neutralize the acid found in cacao. This makes it tastier, but also lowers the flavanol content. And remember that despite all of its potential health benefits, chocolate is also delivering both fat and calories. Be sure to adjust your diet accordingly.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

health

Study's Participants Lost Weight Without Counting Calories

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | July 24th, 2018

Dear Doctor: Is it true that just cutting back on refined sugar, refined grains and highly processed foods can lead to weight loss without cutting calories? If so, count me in. But I could eat a whole lot of whole grains and vegetables before being satisfied. That's still a lot of calories.

Dear Reader: Based on the specifics, we think you're referring to the results of a clinical trial published earlier this year in the Journal of the American Medical Association. The takeaway from the research itself is extremely interesting, but equally fascinating has been how the results have been interpreted in the media. Much of the coverage trumpeted the idea that (at last!) here's a diet where you lose weight without counting calories. And though it's true that caloric restrictions were not built into the study, among the findings was that participants wound up consuming an average of about 500 fewer calories per day.

A team of researchers working in partnership with the National Institutes of Health studied 600 overweight people over the course of a year as they followed eating programs consisting of only high-quality whole foods and beverages. That means heavy on fruits, vegetables, lean proteins, healthful fats, and whole grains and legumes, and few or no highly processed foods. Not only are those loaded with salt, fat, sugars and highly refined carbohydrates, but they've been repeatedly linked to obesity, diabetes, cardiovascular disease and various cancers.

The actual point of the study was whether an individual's genetic makeup or insulin metabolism can predict weight loss or health outcomes. To that end, the study participants were randomly assigned to a diet that was either low in fat, or one that was low in carbs. Over the course of the year the people in the study, all of whom were overweight, also attended 22 counseling sessions with a dietitian.

Just so you know, the conclusion was that genotype and insulin production didn't appear to be predictors of weight loss in either group. Also, neither diet appeared to be superior for weight loss. But what got the most ink was that so many participants lost weight without counting calories. Low-carb participants lost an average of 13 pounds each, while the low-fat group lost an average of 11.7 pounds each. A few people dropped significant weight -- up to 60 pounds -- and some gained weight. And both groups saw drops in waistline measurements, body fat percentage, blood pressure, and fasting levels of insulin and glucose.

So what happened? It appears that by quitting junk foods in favor of a diet of high-quality whole foods, people in the study naturally ate fewer calories without trying to cut back. The fact that all of those health markers also moved in a positive direction speaks volumes for the benefits of this type of eating. What strikes us is that, for all the diets and eating plans and food hacks that have emerged over the decades (centuries, really), it always comes back to the basics -- a balanced diet of whole foods, lean meats, good oils, and plenty of fresh fruit and vegetables.

Now, please, go eat an apple.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

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