health

Managing Lymphedema Takes Sustained Effort and Self-Care

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | February 17th, 2018

Dear Doctor: I'm 26 years old and have been diagnosed with lymphedema in all four limbs. I'm 5 feet 8 inches and weigh 193 pounds. I work out for an hour every morning and am physically active. What else can I do to help my lymphedema?

Dear Reader: Lymphedema is the swelling that occurs in the arms, legs or other parts of the body when the lymphatic system is not functioning properly. It's most common in cancer patients who have had lymph nodes either removed or damaged during surgery or treatment. Swelling caused by injury to the lymphatic system is known as secondary lymphedema. When the swelling occurs independent of surgery or other damage, as in your case, the condition is known as primary lymphedema.

The lymphatic system, which is part of the immune system, is a circulatory system that includes all the tissues and organs that produce, store and carry white blood cells. A crucial part of this system is the network of lymphatic vessels that serve tissues throughout the body. Similar to capillaries, these are thin-walled tubes that drain fluid from the tissues and carry it to the lymph nodes. Unlike capillaries, however, which have the force of the heartbeat to move the blood within them, the lymphatic system is largely dependent on muscle movement to keep things flowing.

The type of lymphedema you have is quite rare. It's an inherited condition in which the lymph vessels have not formed properly. As a result, the protein-rich lymph collects in the layers of soft tissue beneath the skin. This causes swelling in one or both legs, one or both arms, and can also affect the face and trunk.

When you have lymphedema, it's important to seek professional care. The condition puts you at higher risk of developing infections of the skin and underlying tissues, which in turn can lead to abscesses, ulcers and tissue damage. Something as simple as a scratch or cut or insect bite can lead to serious infection.

There is no known cure for lymphedema, and no FDA-approved medication. However, complete decongestive therapy, also known as CDT, is an important tool in controlling the condition. In CDT, a lymphedema therapist leads you through a comprehensive program that includes manual lymphatic drainage, bandaging, the use of compression garments and self-care.

Manual lymphatic drainage, performed by the therapist, uses a feather-light touch to move lymph from the tissues and direct it back into the lymphatic vessels. Compression garments, which are made from flexible fabrics, keep a steady pressure on the affected limb and keep lymph moving.

Self-care includes protecting your limbs from cuts, scrapes, insect bites, overuse and extreme temperatures. Maintaining a healthy body weight is important in managing lymphedema. So is regular exercise, which you've already incorporated into your life. Be sure to run the specifics of your routine by your lymphedema therapist.

Managing lymphedema takes sustained effort and attention. That's why, once again, we're going to urge you to work with specialists in the field. For help finding a lymphedema therapist, visit the National Lymphedema Network at lymphnet.org.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

health

Evidence Suggests Popular Supplements Not Needed for Bone Health

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | February 16th, 2018

Dear Doctor: If vitamin D and calcium don't reduce the risk of bone fractures in older adults, as I recently read, is there any point in taking them?

Dear Reader: For years, the medical community has been touting calcium and vitamin D to prevent fractures; I've been guilty of this practice as well. Although some studies suggested that calcium and vitamin D could help prevent osteoporosis, the degree of improvement was never overwhelming. Still, we held fast to our medical dogma. Now, as you mention, a study has shown the need to look at the data without bias in order to provide more nuanced counsel to our patients.

The research, recently published in the Journal of the American Medical Association (JAMA), reviewed 33 studies -- with a total of 51,145 participants -- assessing the risk of fractures in people taking either calcium alone, vitamin D alone or calcium with vitamin D.

The calcium-only studies included various types of the mineral: calcium citrate, carbonate, malate and gluconate. The seven studies assessing the impact on hip fractures showed no improvement with the use of calcium. In fact, researchers found a 53 percent increase in the risk of hip fractures among people taking calcium. The findings on spinal fractures were more positive. Nine studies assessed that connection, finding a 17 percent decrease in risk with calcium use. Seven studies assessed total fracture rate, finding a 12 percent decrease in risk, but the rate was not considered statistically significant.

The studies that assessed the specific impact of vitamin D similarly failed to produce positive results. In the nine studies of vitamin D use and hip fracture, researchers found a 21 percent increase in the risk of fracture among those taking vitamin D. The studies assessing the impact on spinal fracture and total fractures simply found no benefit.

The studies assessing the impact of calcium combined with vitamin D yielded only marginally better results. Although the seven studies looking at the impact on hip fractures found no reduction in risk, the three studies looking only at spinal fractures did show a 37 percent reduction in risk. The studies that looked at total fracture rate showed a non-significant 10 percent reduction in risk.

The 33 trials varied in length from four months up to seven years. Of note, many studies conducted for longer periods were more likely to show a reduction in the risk of spinal fractures with the use of calcium or vitamin D, which may be because calcium and vitamin D are slow to improve bone density.

The JAMA study did not specifically look at people with osteoporosis. For them, calcium has been shown effective in maintaining bone density. A 1992 study of female nursing home residents (who have a higher likelihood of osteoporosis) found that calcium and vitamin D decreased the rate of hip fracture by 43 percent and the overall fracture rate by 32 percent.

So, if you have osteoporosis, I would recommend calcium and vitamin D. If you're a healthy person without osteoporosis, calcium and vitamin D may produce a slight decrease in the risk of spinal fracture. Overall, however, there seems to be little benefit to this supplementation.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

health

Milk Banks Offer Moms Safely Pasteurized Milk for Babies

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | February 15th, 2018

Dear Doctor: After the hurricane in Houston, a lot of moms donated their breast milk to help the babies. Is that safe?

Dear Reader: For as long as women have been giving birth, they have been sharing breast milk. In earliest history -- references to the practice date back to 2000 B.C. -- this was in the guise of the wet nurse. That is, a lactating woman who breastfed infants who were not her own. If a mother is unable to either breastfeed or express her own milk, the World Health Organization cites donor milk as the next best feeding option.

That's because breast milk is the optimal food for infants. Not only is it a source of probiotics for gut health and antibodies to fight off viruses and bacteria, but studies show that breastfed babies get fewer ear infections, have a lower incidence of obesity, and have a lower risk of conditions like asthma, diabetes and eczema. They are less likely to develop gastroenteritis and diarrhea than babies raised on formula, and have a lower incidence of SIDS, or sudden infant death syndrome.

In recent years, we've seen the advent of milk banks. These are services that collect breast milk donations for use in hospitals for pre-term infants, and for use by women who can't produce enough of their own milk. The donations come from women who have undergone medical screening, often including blood tests. The donor milk is then processed and, at several points in the process, tested for pathogens.

This is important because babies can be exposed to infections and diseases, including the HIV virus, via breast milk. Human milk can contain chemical and environmental contaminants, illegal drugs, and even certain prescription and over-the-counter drugs. And like any food, breast milk must be collected and stored properly to avoid spoilage and microbial contamination.

To answer your question, yes, breast milk that comes from a reputable milk bank is safe. Steps are taken to screen the donors and then properly process the milk. And while many women take part in the hundreds of online private milk-sharing networks that have sprung up around the country, the Food and Drug Administration recommends against them.

The FDA cites the lack of rigorous donor screening as a primary concern. Peer-to-peer networks rely on self-reporting of the donor's physical health. Also, recipients of donor milk within these networks are dependent on each donor's dedication to following good hygiene practices in both collection and storage.

When it comes to processing donor milk, the milk banks use the Holder method of pasteurization. This involves heating the milk to a relatively low temperature, one that kills pathogens but leaves the beneficial qualities of the milk largely intact.

At this time, there are no universal health and safety guidelines for milk sharing, though a few states have established standards for milk banks to adhere to. If you'd like to learn more about milk banks, or want to find one in your area, the Human Milk Banking Association of North America, or HMBANA, can help. It's a voluntary professional association that suggests safety guidelines for donor screening, milk collection, storage, testing and distribution. You can find it online at hmbana.org.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

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