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Less Invasive Procedures Exist for Enlarged Prostate Symptoms

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | August 7th, 2017

Dear Doctor: Is there any treatment besides surgery that can reliably help an older man urinate when he is experiencing difficulty due to prostate enlargement?

Dear Reader: This common problem becomes all the more common as men get older. In fact, 40 to 50 percent of men ages 51 to 60 -- and up to 80 percent of those over 80 -- have prostate enlargement. Slightly more than half suffer symptoms, which include poor urine flow, frequent urination, incomplete emptying of the bladder and, most irritatingly, waking up multiple times at night to urinate. Some of these symptoms can be improved by decreasing alcohol and caffeine and by decreasing evening fluid intake.

Drug treatment is the first line of therapy. Alpha-1 receptor blockers work to relax the smooth muscles in the prostate and the lower portion of the bladder. This relaxation allows the urine to flow more easily from the bladder. The biggest side effect is lightheadedness, because the drug also lowers blood pressure. This lightheadedness has not been reported as much with newer formulations -- tamsulosin, alfuzosin and silodosin -- that improve urine flow and reduce frequency because they're more selective to the urinary tract.

Another option is to decrease prostate size with a medication -- finasteride or dutasteride -- that reduces the formation of the hormone dihydrotestosterone, or DHT. This hormone stimulates the prostate to grow; the medications work by inhibiting the enzyme that produces it. Note, however, that these drugs can take six months to one year to reduce symptoms; the biggest side effects are a lowered libido and, less commonly, erectile dysfunction.

A daily 5-milligram dose of the erectile dysfunction drug Cialis can also reduce symptoms of an enlarged prostate. Lastly, in those who don't retain urine in the bladder, anticholinergic medications such as tolterodine and oxybutynin help relax the bladder and decrease the desire to urinate. The problem with these medications is that they have more side effects, including dry mouth, blurred vision, drowsiness, constipation and impairment of mental function.

Because you mention surgery, I assume that you've already been given medication for your symptoms and are now confronting the prospect of a more radical intervention. The most common surgery for prostate enlargement is a transurethral prostatectomy. In this surgery, a urologist removes a portion of the prostate via the urethra. The transurethral prostatectomy is well-tolerated with minimal side effects, but if you're looking for a less invasive procedure, there are alternatives.

One alternative form of surgery -- known as focused laser ablation -- vaporizes prostate tissue with light waves. This eases symptoms immediately, has less blood loss than traditional surgery and has a recovery time of only two to three days. Although this procedure treats a smaller portion of the prostate, and symptoms may occur again at a later time, early research is supportive of this option. A European study in 2016, for example, showed that the benefits of this treatment lasted more than two years. Similar procedures use water vapor or even microwaves. All of these have fewer side effects than traditional surgery and have been shown to be effective.

Medications are obviously the first choice for symptoms of prostate enlargement. But if those don't work, there are less invasive procedures than traditional surgery.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

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Tips on Avoiding Norovirus if Someone Close to You Is Sick

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | August 5th, 2017

Dear Reader: Some schools in my district are facing an outbreak of norovirus like you wouldn't believe. Why is it spreading so fast? What can I do to protect our family?

Dear Reader: Norovirus, which has earned the nickname "the vomiting bug," is extremely contagious. Add stomach cramps, fever, diarrhea and muscle pain to the list of symptoms and you get a good sense of the misery it causes.

It's the leading cause of gastrointestinal illness in the United States. About 21 million people get norovirus each year. Up to 70,000 of those land in the hospital, and about 800 die. And calling norovirus an "it" is misleading. There are actually many different types of norovirus, so getting sick with one kind doesn't offer protection from others.

The virus is shed in the feces of an infected individual. That means when someone with norovirus follows poor hygiene after a bowel movement, they spread it to everything that they touch. You can pick up norovirus by eating or drinking something handled by a contaminated person, by touching a contaminated surface and later putting your fingers in your mouth, or through close contact with someone who is sick. The virus is also present in a sick person's vomit, which adds another layer of risk when caring for sick children.

One of the reasons that outbreaks are so difficult to contain is that the norovirus is a hardy organism. It's impervious to hot and cold and to many disinfectants. When the virus gains a foothold in crowded and self-contained places like a school, hospital, nursing home or cruise ship, it spreads quickly.

Upping the ante is the fact that it can take up to a week for the norovirus that's already in your body to make you feel sick. And once your symptoms have ended, the virus can be found in your stool for more than two weeks.

So what do you do when norovirus hits nearby? Keep in mind that just because a neighboring school is affected, that doesn't automatically mean your child's will be as well. That said, there are several steps you can take to lessen the risk of infection.

-- All family members should wash their hands often. Use soap and running water and scrub for at least 20 seconds. Always wash after using the bathroom and before preparing food.

-- Carefully wash all fruits, vegetables and seafood before preparing them. Most outbreaks spread in food service areas, so when a norovirus outbreak is nearby, it's not a bad idea for your child to bring her own lunch and snacks to school for the duration.

-- Explain to your kids how the virus is transmitted. That will help them understand these rules: no fingers in the mouth (always a good idea at any time), and no sharing food or drinks with anyone, even if they don't look sick.

-- If someone in the house does become ill, use a bleach-based disinfectant to clean any surfaces contaminated by vomit or diarrhea. Don't forget door and drawer knobs, the fridge and the TV remotes.

-- If you're the one who's sick, don't prepare, cook or serve food for others.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

health

Incidence of Diverticulitis Emblematic of Unhealthy Lifestyles

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | August 4th, 2017

Dear Doctor: I am recovering from a bout of diverticulitis. What are my chances of having another round -- and how can I avoid later episodes? Does the onset increase my risk of serious ailments such as cancer?

Dear Reader: Diverticula are sac-like protrusions from the colon wall. If you were to look inside the colon, diverticula would appear as holes within the colon wall, leading to a bulging sac coming from the intestine. In the United States, diverticula almost always occur near the end of the colon in an area called the sigmoid colon. Chronic pressure in this area from poor intestinal motility, or contractions, leads to the formation of these outcroppings. Diverticula are quite common in the Western world. In one set of screening colonoscopies -- conducted in 624 patients with an average age of 54 -- 42 percent had diverticula. Note that the likelihood of diverticula increases with age.

The presence of diverticula is known as diverticulosis. Inflammation of the diverticula is known as diverticulitis. The latter occurs when increased pressure within a diverticulum leads to a perforation through which bacteria leave the intestine, causing infection. The infection can become so severe that an abscess develops.

Diverticulitis is more prevalent among people with a low-fiber, high-fat diet that includes a lot of red meat. It is also more common among people who are obese, have little physical activity and smoke cigarettes. A common myth, and one I learned in medical school, was that nuts, seeds, corn or popcorn could become trapped in a diverticulum and lead to diverticulitis. A 2008 study not only disproved this myth, it found that the opposite was true among men ages 40 to 75.

A first-time episode of diverticulitis can mimic many of the same symptoms as colon cancer. So unless you've had a colonoscopy in the last year, you should rule out cancer by having a colonoscopy, preferably six to eight weeks after a bout of diverticulitis. One study found that 2.8 percent of people who had a follow-up colonoscopy were then diagnosed with colon cancer. This rate rises for those who have had an abscess related to diverticulitis.

After the first attack of diverticulitis, the likelihood of a second attack is about 33 percent; the likelihood of a third bout after a second bout is also about 33 percent. To help prevent another attack, you need to get the gut moving. That is, increase fiber in your diet. If you can't do this simply by increasing your consumption of high-fiber vegetables, fruits and nuts, then a fiber supplement is in order.

Exercising also will decrease the risk of another attack of diverticulitis. Because diverticulitis occurs more frequently in obese people, losing weight may also decrease your chance of another attack. Decreasing the amount of red meat and fat in your diet may lessen your chances as well.

Nationwide, the incidence of diverticulitis is increasing, especially in people ages 18 to 44. Some of the increase could be attributed to better diagnosis, but the rise is also emblematic of our unhealthy diet and sedentary lifestyle.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

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