On a warm, sunny day, use the sun's rays to disinfect and deodorize your mattress. Completely strip the bed, open the bedroom windows and let the sun's rays pour onto the mattress. The ultraviolet light will help clean the bed. While you're at it, vacuum the top, sides and bottom of the mattress to collect dust, pollen and dander. And wash the mattress cover in hot water to sanitize it as well. That night, you'll have a fresh, clean mattress that will be almost as good as new.