health

Heart Monitor Will Assess Number of PVCs Over 24-Hour Period

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | June 18th, 2018

Dear Doctor: About 15 years ago, while giving blood, I was advised of an irregularity, which my doctor confirmed after an EKG, known as premature ventricular contractions. He told me not to worry, and I've not had any problems. Now I'm 79 and still in good health, but my current doctor had me wear a heart monitor and has now referred me to a cardiologist. Should I be concerned?

Dear Reader: Premature ventricular contractions (PVCs) are very common. In healthy people without any evidence of heart disease, 50-54 percent will be found to have some degree of PVCs when monitored for 24 hours. Here are the basics: Electrical impulses normally begin in the atria of the heart before they make their way down to the ventricles. This leads to the atria contracting first, followed by the ventricles. However, PVCs are ventricular contractions that bypass the atrial beat, leading to an extra heartbeat.

PVCs are more common in men than in women, increase in frequency with age and are more common in African-Americans. Lastly, they are more common in people with structural heart disease, especially those with congestive heart failure and those who have had heart attacks.

Most PVCs are not felt. It sounds as if you weren't having symptoms from the PVCs, but rather that they were simply noted on examination by your doctor. When patients feel PVCs, they often describe a sensation of a pause or a skipped beat. People also sometimes feel that the heart is beating hard or fast or that they have a strong pulsation in the neck. Sometimes PVCs can cause lightheadedness and anxiety. Very frequent PVCs have been associated with heart failure.

Sometimes, concerns about PVCs are related to their frequency, especially if they were sporadic and then become more numerous. Increased frequency of PVCs has been associated with an increase in mortality. This was illustrated in a 2006 study of 15,070 patients ages 45 to 64 who had no history of heart disease and who had a two-minute electrocardiogram performed. Those with one or more PVCs on the electrocardiogram had twice the likelihood of dying of coronary heart disease.

Similarly, a 2007 study of 45,402 veterans showed that 3.8 percent of the veterans studied had PVCs on a routine electrocardiogram -- and that the PVCs were associated with a nearly twofold increase in mortality. Note that routine electrocardiograms only last for 10 seconds, so detecting a PVC on an electrocardiogram suggests a very high frequency over a 24-hour period.

Studies over a 24-hour period have also shown that more frequent PVCs -- recorded in this way -- are also linked to an increased risk of heart failure and heart-related deaths, but the risk is greater when a PVC is seen on a routine electrocardiogram.

The heart monitor that your doctor recommended should pick up the number of PVCs over a 24-hour period. If the PVCs are frequent, the cardiologist may want to do other studies, like an echocardiogram, to determine whether there is any structural damage to the heart.

Treatment of PVCs for people with symptoms include calcium channel blockers and beta blockers. If these don't help control symptoms or if there is structural heart disease, anti-arrhythmic medication or electrical destruction of the area of heart that is causing PVCs may be necessary.

I would have some degree of concern regarding PVCs, but the results of the 24-hour monitor and your visit to the cardiologist will provide more information.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

health

Potential Mumps Outbreak Feared After Exposure to Virus at Event

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | June 16th, 2018

Dear Doctor: Are mumps really dangerous? Thousands of people apparently may have been exposed at a cheerleading event a few months ago, which seemed to upset public health officials. My kids have been vaccinated, but I'm not sure if I have been, or even if I've had the disease. Should I be concerned?

Dear Reader: Mumps is a viral infection that affects the parotid glands, which are one of three sets of salivary glands. The virus spreads when tiny airborne droplets of saliva are released during a cough, a sneeze and even through speech. These droplets, which contain the active virus, can then be inhaled by anyone in the infected person's vicinity. The virus can also linger on hard surfaces that those aerosolized droplets have landed on, so touching an object in an infected person's room, or sharing a sick person's food, glassware, dishes or cutlery can put anyone without immunity at risk.

In the incident you mentioned, tens of thousands of people were exposed to mumps when they attended the National Cheerleaders Association All-Star National Championship, which was held in Dallas. An attendee from outside the state turned out to be sick with mumps and was in the contagious stage of the illness. Someone with mumps is capable of spreading the virus anywhere from a few days before and up to five days after the onset of parotitis, which is the characteristic facial swelling that often accompanies the illness. The first symptoms of mumps typically appear 16 to 18 days after infection, though it can be as soon as 12 days, or as many as 25 days.

Mumps is not considered to be dangerous in the majority of cases. But as with any viral illness, it does take a toll on the body. In addition to the swelling of the salivary glands, symptoms can include fever, headache, muscle aches, tiredness, general malaise and loss of appetite. Up to 40 percent of infected individuals will have few or no symptoms. About one-third of males with the mumps who are post-puberty will also experience pain or swelling of the testicles. Complications, which are thankfully rare, can include deafness, infertility, meningitis and encephalitis.

There is no targeted cure for mumps at this time, so treatment consists of addressing specific symptoms. In most people, the disease will run its course in two to three weeks. The best form of protection against mumps is the MMR vaccine, which targets measles and rubella as well as mumps. The Centers for Disease Control and Prevention recommends children get two doses of the MMR vaccine, first at 12 to 15 months of age, and again at 4 to 6 years of age. And because immunity appears to wane over time, some epidemiologists now recommend a third dose of the vaccine for individuals living near a mumps outbreak. You can track current mumps outbreaks at cdc.gov/mumps/outbreaks.html.

Since you don't know your immunity status, we recommend that you contact your primary care physician, who can check your immunity through bloodwork.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

health

Slowly Progressing Cataracts May Not Affect Vision at First

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | June 15th, 2018

Dear Doctor: I'm 62, and during my routine eye exam yesterday, the doctor said that I am showing the first signs of cataracts. I know that cataracts develop slowly, but she wants to see me in six months. Does a six-month wait make sense?

Dear Reader: As you noted, cataracts -- which cloud the lens of the eye -- are slow to develop, with initial symptoms amounting only to difficulties with night vision or an ability to read highway signs. But over the years, untreated cataracts can lead to blindness. Before the advent of simple surgical procedures to remove the opacified lens and replace it with an artificial lens, cataracts were the most common cause of blindness in the United States. They are still the most common cause of blindness worldwide, leaving nearly 15 million people unable to see.

Cataracts develop because the cells of the lens create a complex lattice that continues to form even after the cells die. Because the lens does not shed these dead cells, they are susceptible to damage without any ability for repair. Most of this damage simply occurs with age, but other factors can be involved. Smoking, alcohol, diabetes, damage from sunlight and poor nutrition can all cause cellular damage that increases the risk for cataracts. So, too, can exposure to oral or high-dose inhaled steroids.

Diets that are high in fruits and vegetables -- specifically those containing high amounts of the compounds lutein and zeaxanthin -- are associated with a lower risk of developing cataracts.

Your eye doctor, in addition to monitoring your cataracts, has also probably tested for glaucoma. On occasion, cataracts can lead to increased pressure in the eye and glaucoma.

If your cataracts are slowly progressing, I agree with your doctor about re-evaluating them at a later time. If the cataracts are creating glaucoma, or if your doctor cannot evaluate your retina because the lenses are too cloudy, that may be an indication to remove the lenses now. Otherwise, surgery to remove cataracts is based on how they're affecting vision -- meaning, how they impact daily life.

Previously, ophthalmologists didn't recommend cataract surgery until the cataract was considered "ripe" for removal. This philosophy was in place for many years because previous surgical techniques for cataracts led to many more complications than today's techniques. However, cataract surgery today is a simple outpatient procedure, often done without anesthesia. In addition, new focal lenses can be implanted to provide better reading or distance vision.

Simply put, you should have your cataracts removed if you're having trouble reading road signs, seeing at night or deciphering fine print. If this is not occurring, you can wait -- even for many years. It's possible that removing cataracts too early could potentially expose the retina to more light damage and increase the risk of macular degeneration, but that association is from observational data, not clinical trials.

Many of my patients who have cataracts wait an entire year to have their eyes rechecked, so six months should be fine. And remember: To decrease the progression of cataracts, avoid smoking, cut back on alcohol (if you drink) and follow a good diet. This will not only help your eyes, but also the rest of your body.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

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