health

Surgical Procedure Can Lessen Symptoms of Neurological Condition

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | October 2nd, 2017

Dear Doctor: What can be done for normal pressure hydrocephalus? My dad was diagnosed with this condition six months ago after developing severe gait problems, urinary urgency and memory issues. He has a few other physical issues, but is otherwise healthy.

Dear Reader: I'm glad your father's doctor was able to pinpoint the source of his symptoms. Because normal pressure hydrocephalus (NPH) is a rare condition, with a gradual onset of symptoms, it can be difficult to diagnose. The annual incidence is between 1.19 and 3.4 per 100,000 people. This form of hydrocephalus, or "water on the brain," can occur after a head trauma, stroke or brain tumor, but in some cases, the cause is unknown. To understand the condition takes an understanding of the fluid that bathes the entire brain and that flows through its ventricles, or cavities.

This fluid, called cerebrospinal fluid, is produced by the lateral ventricles of the brain and is eventually reabsorbed into the body through veins within the brain. If the body has difficulty reabsorbing the fluid, the fluid increases within the ventricles, putting pressure on the brain itself. This pressure damages the nerves and nerve connections within the brain. Initial symptoms include difficulty walking, as if a person's feet are glued to the floor, and with the feet outwardly rotated. Patients also have difficulty turning and can lose stability and fall.

People with the condition also have concentration problems, slowed mental abilities and a lack of concern for their disability. Lastly, they have urinary urgency, which can lead to urinary incontinence.

Once you have a diagnosis, however, you can move to treatment, which consists of decreasing the level of cerebrospinal fluid within the skull.

This is done through a ventriculoperitoneal (VP) shunt. After drilling a small hole in the skull, a neurosurgeon places a catheter into the lateral ventricle within the brain. That catheter is attached to a valve behind the ear. From the valve, another catheter is guided down the neck and into either the chest or abdomen. When the pressure builds in the ventricle, the valve opens, draining the fluid from the brain into the chest or abdomen, depending where the second catheter ends. This fluid is then reabsorbed by the body.

The effectiveness of shunts varies widely, studies suggest. The greatest patient improvements seem to be in the ability to get up out of a chair and walk. Memory and reaction time also can improve after shunting, as can urinary symptoms. However, if memory deficits are to the point of moderate to severe dementia, then a shunt may not help that aspect.

One important thing to note is that the longer the patient has symptoms, the less likely a shunt will provide benefit. This is especially true if symptoms have been present for more than two years.

VP shunts can have many complications, including a risk of bleeding, brain infections, seizures, malfunction of the shunt or an over-drainage of cerebrospinal fluid. The rates of these complications are decreasing, but still can occur up to a third of the time.

Based on what you've told me, the cause of your father's hydrocephalus is unclear. Nonetheless, if the shunt is stable, patients like your father can have sustained benefit for many years.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

health

When Going to Indoor Pool, Practice Good Etiquette

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | September 30th, 2017

Dear Doctor: With cooler weather here in Minnesota, our kids, who love swimming, are switching from the lake to the pool at our local Y. Just how dangerous is it to swim in a public pool? I keep hearing there's a bug that chlorine doesn't kill.

Dear Reader: Any time you share a common space, whether with one other person or a crowd, you run the risk of being exposed to whatever germs, viruses, parasites, bacteria, molds or other environmental hitchhikers they may have brought along. Unsurprisingly, this applies to the public swimming pool, where diarrhea is the most common recreational water illness. And while chlorine significantly reduces the potential health risks posed by public swimming pools, it's not a guarantee.

When used in the proper amounts needed to maintain a consistent pH, chlorine eliminates all manner of nasty bugs. Chlorinated pool water kills E. coli in less than a minute. Norovirus and Hepatitis A perish after 15 minutes. Giardia lasts for only about 45 minutes in properly chlorinated water.

However, Cryptosporidium, a microscopic parasite that causes a diarrheal disease that can last two to three weeks, is different. Due to a protective coating during part of its life cycle (we'll get to that in a minute), Cryptosporidium, commonly known as Crypto, can survive for up to 10 days in the pool, even one that is properly maintained. According to the Centers for Disease Control and Prevention, in recent years Cryptosporidium has become the leading cause of swimming pool-related outbreaks of diarrheal illness in the United States.

Any time an infected person passes any amount of feces into the water, they're also releasing the parasite. At this point in its life cycle, Crypto is encased in a hardy, thick-walled shell, a form known as an oocyst. When a swimmer somehow swallows or inhales water that contains an oocyst, the parasite enters the body. It then moves through the digestive system and into the cells lining the gut, where it begins to multiply rapidly. Up to 100 million oocysts can be released with a single bowel movement.

It's not just swimming pools that are at risk when used by people infected with Crypto. Water parks, hot tubs and recreational fountains can become contaminated as well. So can lakes and the ocean, although there, with the vastly larger volume of water, the odds of contact are somewhat reduced.

Ironically, the very chemicals used to keep swimming pool water clean can themselves become health hazards. The scent of chlorine, particularly in indoor pools where adequate ventilation can be difficult, is a sign that chloramines, a compound present in chlorinated water, has turned to gas. Chloramines can cause nasal irritation, coughing or wheezing, and can even trigger asthma attacks.

Your best defense is insisting on good pool etiquette.

-- Choose a pool that insists patrons take a pre-swim shower.

-- Make sure that anyone with diarrhea never goes into the pool.

-- If you have young children, take them on frequent bathroom breaks.

-- Remember: Diapers don't belong in swimming pools.

-- Any time you see feces in the water, or when the smell of chlorine becomes strong, tell pool management.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

health

Risks Involved in Getting Colonoscopy Are Minor

Ask the Doctors by by Eve Glazier, M.D. and Elizabeth Ko, M.D
by Eve Glazier, M.D. and Elizabeth Ko, M.D
Ask the Doctors | September 29th, 2017

Dear Doctor: What are the risks of a colonoscopy? Based on what I know about the procedure, it seems entirely likely that the colon could be damaged.

Dear Reader: Many people share your concerns, especially if they've never undergone the procedure. The first thing you should know is that colonoscopy is the gold standard in colorectal cancer screening. It can locate and remove polyps that may later increase the risk of colon cancer, and it's critical to the diagnosis of colon cancer in its early stages, when the disease is most curable. Colonoscopy may not be perfect, but studies have found decreased mortality rates among people who have a colonoscopy between the ages 50 and 75. That being said, the colonoscopy is not an entirely benign test.

First, there is the bowel preparation necessary to clear the colon. For some people, the medications to empty the bowels can cause abdominal bloating, pain, nausea, vomiting and alterations of the body's electrolytes.

Many patients who undergo colonoscopies are sedated prior to the procedure, and in people with a previous history of heart disease or severe lung disease, the sedatives can lead to abnormal heart rhythms, a drop in blood pressure and a decrease in the blood oxygen level. These problems are rare, but those with heart and lung disease should be aware of the risks.

After the preparation, the gastroenterologist inserts the scope and adds air to distend the colon, an act called insufflation. Here's where the primary risk comes in: The scope and the insufflation of the colon can indeed lead to perforation (tearing) of the colon. Perforations are more likely to occur after the age of 75; the perforation rate is nearly 6 times higher in that age group than in people under 60. Also, people who are ill from other diseases, such as heart failure, diabetes or cancer, have a greater rate of perforation. So, too, do those with diverticula of the colon (small pouches caused by weakness in the colon wall). Removal of a large polyp also increases the risk of perforation. Large perforations require surgical repair, while small perforations can be managed without surgery. Worldwide, perforation rates from a screening colonoscopy occur once in every 1,428 colonoscopies.

Other risks arise from polyp removal -- standard procedure upon their discovery -- because it can cause bleeding, and this risk increases in patients with a bleeding disorder. To reduce the likelihood of bleeding, all patients having a colonoscopy should stop taking any blood thinners several days beforehand.

As for infections, this complication is very rare and is related to defective equipment or improper cleaning of equipment.

The overall death rate from both screening and diagnostic colonoscopies is about 1 in 35,000, and the rates are continuing to decline.

Although there is a risk from colonoscopies, you should be aware that the risk of colon cancer is much higher -- more than 40 cases per 100,000 people each year in the United States -- and the colonoscopy is essential in the diagnosis of this and other colon diseases. If your doctor says you should have one, I would urge you to follow that advice.

(Send your questions to askthedoctors@mednet.ucla.edu, or write: Ask the Doctors, c/o Media Relations, UCLA Health, 924 Westwood Blvd., Suite 350, Los Angeles, CA, 90095. Owing to the volume of mail, personal replies cannot be provided.)

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